Sodium chloride 0.45 and dextrose 5 – Sodium chloride 0.45% and dextrose 5% is a sterile, nonpyrogenic solution commonly used in various medical applications. This article delves into the composition, properties, medical uses, preparation, administration, safety, and comparison of this solution with other intravenous fluids.
Composed of sodium chloride, an electrolyte, and dextrose, a carbohydrate, this solution plays a crucial role in maintaining fluid and electrolyte balance, providing calories, and supporting various physiological processes.
Sodium Chloride 0.45 and Dextrose 5
Sodium chloride 0.45 and dextrose 5 (NS0.45/D5) is a sterile, nonpyrogenic, and hypertonic solution used for various medical purposes, including hydration, electrolyte replacement, and as a vehicle for drug administration.
Composition and Properties, Sodium chloride 0.45 and dextrose 5
NS0.45/D5 is a combination of sodium chloride (NaCl) and dextrose (D5) in water. The chemical composition of NS0.45/D5 is as follows:
- Sodium chloride (NaCl): 0.45% (77 mEq/L sodium, 77 mEq/L chloride)
- Dextrose (D5): 5% (50 g/L)
The physical properties of NS0.45/D5 include:
- pH: 4.5-7.0
- Osmolarity: 273 mOsm/L
- Viscosity: Slightly viscous
Sodium chloride provides electrolytes (sodium and chloride) to the body, while dextrose provides energy as a source of carbohydrates.
General Inquiries
What is the pH of sodium chloride 0.45% and dextrose 5%?
The pH of sodium chloride 0.45% and dextrose 5% is approximately 5.6.
What is the osmolarity of sodium chloride 0.45% and dextrose 5%?
The osmolarity of sodium chloride 0.45% and dextrose 5% is approximately 308 mOsm/L.
What are the contraindications for using sodium chloride 0.45% and dextrose 5%?
Sodium chloride 0.45% and dextrose 5% is contraindicated in patients with hypernatremia, hyperchloremia, hyperglycemia, or severe renal impairment.
